Apply in the evening after cleansing and toning, and before moisturizer. If new to retinol, start twice a week, 2–3 days apart, gradually increasing to every other night, then nightly as tolerated. Apply to the entire face, avoiding the eyes; if contact occurs, rinse thoroughly with water.

Caution: Do not use if pregnant, lactating, or planning pregnancy. Mild redness, peeling, or irritation is normal. Use daily SPF 30+ and limit sun exposure while using this product and for one week after discontinuing.